Nevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin syndrome, is a genetic condition that increases the risk of developing multiple basal cell carcinomas, a type of skin cancer. It is caused by mutations in the PTCH1 gene, which plays a role in cell growth and development. Individuals with NBCCS may also experience other abnormalities, including jaw cysts, skeletal anomalies, and an increased risk of certain tumors. People with NBCCS often show signs early in life, such as skin lesions or jaw cysts. Regular monitoring and early intervention are essential for managing the condition and reducing cancer risk. Genetic counseling can help affected individuals and their families understand the syndrome and its implications.