PTCH1 is a gene located on chromosome 9 that plays a crucial role in the Hedgehog signaling pathway, which is important for cell growth and development. It encodes a protein that helps regulate this pathway, ensuring that cells receive the correct signals for proper functioning. Mutations in the PTCH1 gene can lead to various health issues, including Gorlin syndrome, a genetic condition characterized by an increased risk of developing certain types of tumors and other abnormalities. Understanding PTCH1 is essential for studying developmental biology and cancer research.