Nevoid Basal Cell Carcinoma Syndrome
Nevoid Basal Cell Carcinoma Syndrome (NBCCS), also known as Gorlin syndrome, is a genetic condition that increases the risk of developing multiple basal cell carcinomas, a type of skin cancer. It is caused by mutations in the PTCH1 gene, which plays a role in cell growth and development. Individuals with NBCCS may also experience other abnormalities, including jaw cysts, skeletal anomalies, and an increased risk of certain tumors.
People with NBCCS often show signs of the syndrome in their teenage years or early adulthood. Regular skin examinations and monitoring for other associated conditions are essential for managing the syndrome. Early detection and treatment of basal cell carcinomas can help reduce complications and improve outcomes for affected individuals.