Alpha-Thalassemia is a blood disorder caused by a genetic mutation that affects the production of hemoglobin, the protein in red blood cells that carries oxygen. This condition occurs when one or more of the four alpha-globin genes are missing or mutated, leading to reduced hemoglobin levels and resulting in anemia. Symptoms can range from mild to severe, depending on the number of affected genes. There are two main types of Alpha-Thalassemia: Alpha-Thalassemia Trait, which usually causes mild symptoms, and Hemoglobin H Disease or Alpha-Thalassemia Major, which can lead to more serious health issues. Diagnosis typically involves blood tests, and treatment may include regular blood transfusions or other supportive care.