Zinc metalloproteinases are a group of enzymes that play a crucial role in breaking down proteins. They contain zinc ions in their active sites, which help catalyze the hydrolysis of peptide bonds. These enzymes are involved in various biological processes, including tissue remodeling, immune response, and cell signaling. These metalloproteinases are classified into different families, such as matrix metalloproteinases (MMPs) and metalloproteinase-disintegrins (ADAMs). They are essential for normal physiological functions but can also contribute to disease processes, including cancer and inflammatory conditions, when their regulation is disrupted.