matrix metalloproteinases
Matrix metalloproteinases (MMPs) are a group of enzymes that play a crucial role in the breakdown of proteins in the extracellular matrix, which provides structural support to tissues. They are involved in various physiological processes, including tissue remodeling, wound healing, and embryogenesis. MMPs help maintain the balance between the formation and degradation of the extracellular matrix.
These enzymes are also implicated in several pathological conditions, such as cancer, arthritis, and cardiovascular diseases. Dysregulation of MMP activity can lead to excessive tissue degradation or inadequate repair, contributing to disease progression. Understanding MMPs is essential for developing targeted therapies for these conditions.