Matrix Metalloproteinases
Matrix Metalloproteinases (MMPs) are a group of enzymes that play a crucial role in the breakdown of proteins in the extracellular matrix, which provides structural support to tissues. They are involved in various physiological processes, including tissue remodeling, wound healing, and inflammation. MMPs help maintain the balance between the formation and degradation of the extracellular matrix.
These enzymes are produced by various cell types, including fibroblasts, macrophages, and chondrocytes. Dysregulation of MMP activity can lead to several diseases, such as arthritis, cancer, and cardiovascular disorders. Understanding MMPs is essential for developing potential therapeutic strategies to treat these conditions.