Metalloproteinase inhibitors are substances that block the activity of metalloproteinases, which are enzymes that break down proteins in the body. These enzymes play a crucial role in various physiological processes, including tissue remodeling and wound healing. However, excessive activity of metalloproteinases can lead to diseases such as arthritis and cancer. By inhibiting metalloproteinases, these inhibitors can help control tissue degradation and inflammation. They are being researched for their potential therapeutic applications in treating conditions like cardiovascular diseases and cancer. Understanding how these inhibitors work can lead to the development of new treatments that improve patient outcomes.