The PI3K/Akt signaling pathway is a crucial cellular signaling mechanism that regulates various cellular functions, including growth, survival, and metabolism. It begins when phosphoinositide 3-kinase (PI3K) is activated by growth factors or hormones, leading to the production of phosphatidylinositol (3,4,5)-trisphosphate (PIP3). This molecule then recruits and activates Akt, a protein kinase that plays a key role in promoting cell survival and growth. Once activated, Akt phosphorylates multiple downstream targets, influencing processes such as protein synthesis and glucose metabolism. Dysregulation of the PI3K/Akt pathway is often associated with various diseases, including cancer, making it a significant focus for therapeutic research. Understanding this pathway is essential for developing targeted treatments.