Phosphoinositide 3-kinase (PI3K) is an enzyme that plays a crucial role in cellular signaling pathways. It is involved in various cellular processes, including growth, proliferation, and survival. PI3K is activated by various receptors, such as growth factor receptors, leading to the production of phosphoinositides, which are important for signaling within the cell. The activity of PI3K is essential for many physiological functions, and its dysregulation is associated with several diseases, including cancer and metabolic disorders. Researchers study PI3K to understand its role in these conditions and to develop targeted therapies that can modulate its activity for better health outcomes.