Keratoderma is a skin condition characterized by thickened areas of skin, often found on the palms of the hands and soles of the feet. This thickening occurs due to an increase in keratin, a protein that helps protect the skin. Keratoderma can be inherited or acquired and may vary in severity and appearance. There are different types of keratoderma, including palmoplantar keratoderma and epidermolytic keratoderma. Treatment options may include topical therapies, such as creams or ointments, and in some cases, more advanced treatments like laser therapy. Regular dermatological care is essential for managing symptoms.