Palmoplantar Keratoderma is a skin condition characterized by thickening of the skin on the palms of the hands and the soles of the feet. This thickening can lead to discomfort, pain, and difficulty in movement. The condition can be inherited or acquired and may vary in severity among individuals. The exact cause of Palmoplantar Keratoderma can differ, with some cases linked to genetic factors, while others may arise from environmental influences or underlying health issues. Treatment options often focus on managing symptoms and may include topical therapies, moisturizers, or, in some cases, systemic medications.