Epidermolytic Hyperkeratosis is a rare genetic skin disorder characterized by thickened skin and blister formation. It results from mutations in the genes responsible for producing keratin, a protein that helps maintain skin structure and integrity. This condition typically presents at birth or in early childhood, leading to areas of red, scaly skin that can be painful. The condition is classified as an autosomal dominant disorder, meaning it can be inherited from just one affected parent. While there is no cure, treatment focuses on managing symptoms, such as using moisturizers and topical therapies to improve skin appearance and comfort.