Gardner syndrome
Gardner syndrome is a genetic disorder that is part of the familial adenomatous polyposis (FAP) spectrum. It is characterized by the development of multiple colorectal polyps, which can lead to colorectal cancer if not monitored and treated. In addition to polyps, individuals with Gardner syndrome may also have various tumors, including osteomas (bone growths) and epidermoid cysts.
The condition is caused by mutations in the APC gene, which is crucial for regulating cell growth. Gardner syndrome is inherited in an autosomal dominant pattern, meaning that only one copy of the mutated gene from an affected parent can lead to the disorder in their offspring. Regular screening and preventive measures are essential for managing the risks associated with this syndrome.