Familial Mediterranean Fever
Familial Mediterranean Fever (FMF) is a genetic disorder that primarily affects people of Mediterranean descent, including those of Armenian, Jewish, Arab, and Turkish backgrounds. It is characterized by recurrent episodes of fever and painful inflammation in the abdomen, chest, or joints. These episodes can last from a few hours to several days and may occur at irregular intervals.
The condition is caused by mutations in the MEFV gene, which plays a role in regulating inflammation. Treatment typically involves the use of colchicine, a medication that helps reduce the frequency and severity of attacks, improving the quality of life for those affected.