Betanodavirus is a type of virus that primarily infects fish, particularly those in the family Coryphaenidae. It is known to cause significant diseases in aquaculture, leading to economic losses. The virus can affect various species, including barramundi and sea bass, resulting in symptoms like lesions and neurological issues. This virus is part of the Nodaviridae family and is characterized by its single-stranded RNA genome. Transmission typically occurs through direct contact or contaminated water. Effective management strategies, including biosecurity measures and vaccination, are essential to control outbreaks in fish farming environments.