ADAMTS-3 is a member of the ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) family of enzymes. It plays a crucial role in the degradation of extracellular matrix components, particularly versican, which is important for tissue structure and function. This enzyme is primarily expressed in various tissues, including the heart, lung, and skin. Research suggests that ADAMTS-3 may be involved in processes such as tissue remodeling and inflammation, making it a potential target for therapeutic interventions in diseases related to extracellular matrix dysfunction.