autosomal dominant polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the formation of numerous cysts in the kidneys. These cysts can grow large and disrupt normal kidney function, leading to complications such as high blood pressure and kidney failure. The condition is caused by mutations in specific genes, primarily PKD1 and PKD2, which are inherited in an autosomal dominant pattern.
ADPKD affects both men and women equally and symptoms often appear in adulthood. Common signs include abdominal pain, blood in urine, and frequent urinary tract infections. Regular monitoring and management are essential to address complications and maintain kidney health.