TIMP-4, or Tissue Inhibitor of Metalloproteinases 4, is a protein that plays a crucial role in regulating the activity of metalloproteinases, which are enzymes involved in the breakdown of extracellular matrix components. By inhibiting these enzymes, TIMP-4 helps maintain the structural integrity of tissues and prevents excessive tissue remodeling. TIMP-4 is part of a family of TIMPs that work together to control various biological processes, including wound healing and inflammation. Abnormal levels of TIMP-4 have been associated with several diseases, including cancer and cardiovascular disorders, highlighting its importance in health and disease management.