TIMP-3, or Tissue Inhibitor of Metalloproteinases-3, is a protein that plays a crucial role in regulating the activity of enzymes known as metalloproteinases. These enzymes are involved in the breakdown of extracellular matrix components, which are essential for tissue remodeling and repair. By inhibiting these enzymes, TIMP-3 helps maintain the balance between tissue formation and degradation. TIMP-3 is produced by various cell types and is found in many tissues throughout the body. Its functions are important in processes such as wound healing, inflammation, and cancer progression. Abnormal levels of TIMP-3 can be associated with various diseases, highlighting its significance in health and disease management.