TIMP-2, or Tissue Inhibitor of Metalloproteinases-2, is a protein that plays a crucial role in regulating the activity of enzymes known as metalloproteinases. These enzymes are involved in the breakdown of extracellular matrix components, which is important for processes like tissue remodeling and wound healing. By inhibiting these enzymes, TIMP-2 helps maintain the balance between tissue formation and degradation. TIMP-2 is produced by various cell types and is found in many tissues throughout the body. Its levels can be influenced by factors such as inflammation and disease. Research has shown that TIMP-2 may have implications in conditions like cancer and cardiovascular diseases, making it a subject of interest in medical studies.