Princess Maria Theresa of Naples and Sicily was born on January 6, 1772, as the daughter of King Ferdinand I of the Two Sicilies and Maria Carolina of Austria. She was a member of the House of Bourbon and played a significant role in the royal family of Naples and Sicily during her lifetime. In 1790, Maria Theresa married Duke Francesco d'Este, which strengthened the ties between the Bourbon and Este families. Throughout her life, she was involved in various cultural and social activities, contributing to the arts and education in her region until her death on April 13, 1807.