Primary amenorrhea is a medical condition characterized by the absence of menstruation in individuals by the age of 16, despite the presence of secondary sexual characteristics. It can occur due to various factors, including genetic disorders, hormonal imbalances, or anatomical abnormalities in the reproductive system. Diagnosis typically involves a thorough medical history, physical examination, and various tests to determine the underlying cause. Treatment options vary based on the cause and may include hormone therapy or surgical interventions to address any anatomical issues. Early diagnosis and management are essential for overall health and well-being.