Percutaneous Epididymal Sperm Aspiration (PESA) is a medical procedure used to collect sperm directly from the epididymis, a coiled tube located behind each testis. This technique is often employed in cases of male infertility, particularly when there is a blockage or absence of sperm in the ejaculate. PESA is minimally invasive and typically performed under local anesthesia. During the procedure, a thin needle is inserted into the epididymis to extract sperm. The collected sperm can then be used for assisted reproductive technologies, such as in vitro fertilization (IVF). PESA is a valuable option for men who wish to father children but face challenges related to sperm production or transport.