The PTCH1 gene is a crucial gene located on chromosome 9 that plays a significant role in the Hedgehog signaling pathway, which is important for cell growth and development. It encodes a protein that acts as a receptor for Hedgehog proteins, which are essential for regulating various developmental processes in the body. Mutations in the PTCH1 gene can lead to several health issues, including Gorlin syndrome, a genetic condition characterized by an increased risk of developing certain types of tumors and other abnormalities. Understanding the function of the PTCH1 gene is vital for studying these conditions and developing potential treatments.