Hedgehog signaling pathway
The Hedgehog signaling pathway is a crucial communication system in cells that helps regulate development and tissue growth. It plays a significant role in processes like cell differentiation, proliferation, and patterning during embryonic development. The pathway is named after the Hedgehog gene, which was first discovered in Drosophila, a type of fruit fly.
When the Hedgehog protein binds to its receptor, it triggers a cascade of events that ultimately influences gene expression. This pathway is essential for proper formation of various body structures and is also involved in maintaining stem cell populations. Dysregulation of the Hedgehog signaling can lead to developmental disorders and certain types of cancer.