Li-Fraumeni syndrome is a rare genetic disorder that increases the risk of developing several types of cancer, often at a young age. It is caused by mutations in the TP53 gene, which normally helps control cell growth and prevent tumor formation. People with this syndrome may face a higher likelihood of cancers such as breast cancer, sarcomas, and brain tumors. Individuals with Li-Fraumeni syndrome often have a family history of cancer, making it important for them to undergo regular screenings. Genetic counseling can help families understand their risks and make informed decisions about monitoring and prevention strategies. Early detection is crucial for improving outcomes in those affected.