Holoprosencephaly is a rare congenital brain disorder that occurs when the forebrain fails to properly divide into two hemispheres during early fetal development. This condition can lead to various physical and cognitive challenges, depending on the severity of the malformation. Symptoms may include facial abnormalities, developmental delays, and issues with coordination. The exact cause of holoprosencephaly is often unknown, but it can be associated with genetic factors, maternal diabetes, or exposure to certain environmental toxins during pregnancy. Diagnosis typically involves imaging techniques like ultrasound or MRI, and treatment focuses on managing symptoms and providing supportive care.