HPV 16, or Human Papillomavirus type 16, is a strain of the HPV virus known for its association with certain cancers. It is one of the high-risk types of HPV that can lead to cervical cancer, as well as cancers of the throat, anus, and penis. HPV 16 is transmitted through intimate skin-to-skin contact, often during sexual activity. Most people infected with HPV 16 do not show symptoms and may clear the virus naturally. However, persistent infection can lead to cellular changes that may develop into cancer over time. Vaccines are available to help prevent HPV infections, including HPV 16.