Autoinflammatory syndromes are a group of disorders characterized by recurrent episodes of inflammation without the presence of infection. These conditions arise from genetic mutations that affect the body's immune response, leading to symptoms such as fever, rash, and joint pain. Common examples include Familial Mediterranean Fever and Cryopyrin-Associated Periodic Syndromes. Patients with autoinflammatory syndromes often experience periodic flares of symptoms, which can vary in duration and intensity. Treatment typically focuses on managing inflammation and preventing flare-ups, often using medications like nonsteroidal anti-inflammatory drugs (NSAIDs) or biologics to help control the immune response.