Thiazides are a class of medications primarily used to treat high blood pressure and fluid retention. They work by helping the kidneys remove excess sodium and water from the body, which lowers blood volume and, in turn, reduces blood pressure. Common examples include hydrochlorothiazide and chlorthalidone. These medications are often prescribed alongside other treatments for conditions like heart failure and certain types of kidney disorders. While generally effective, thiazides can lead to side effects such as electrolyte imbalances, increased urination, and, in some cases, elevated blood sugar levels. Regular monitoring is essential for those on these medications.