Severe depression, also known as major depressive disorder, is a mental health condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest in activities once enjoyed. It can significantly impair daily functioning, affecting work, relationships, and overall quality of life. Symptoms may include changes in appetite, sleep disturbances, fatigue, and difficulty concentrating. This condition often requires professional treatment, which may include therapy, medication, or a combination of both. Severe depression can also lead to physical health issues and, in extreme cases, thoughts of self-harm or suicide. Early intervention is crucial for effective management and recovery.