porphyria cutanea tarda
Porphyria cutanea tarda (PCT) is a type of porphyria, a group of disorders caused by the buildup of porphyrins in the body. PCT primarily affects the skin, leading to symptoms such as blisters, fragility, and scarring, particularly on sun-exposed areas. It is often triggered by factors like excessive sun exposure, alcohol consumption, and certain medications.
The condition is linked to a deficiency in the enzyme uroporphyrinogen decarboxylase, which is essential for porphyrin metabolism. PCT can be diagnosed through blood and urine tests that measure porphyrin levels. Treatment typically involves avoiding triggers, using sun protection, and sometimes medications to manage symptoms.