Lupus erythematosus is an autoimmune disease where the body's immune system mistakenly attacks its own tissues. This can lead to inflammation and damage in various organs, including the skin, joints, kidneys, and heart. Symptoms often include fatigue, joint pain, skin rashes, and fever, which can vary in severity and may come and go. There are different types of lupus, with systemic lupus erythematosus (SLE) being the most common. Diagnosis typically involves a combination of medical history, physical exams, and laboratory tests. While there is no cure, treatments are available to help manage symptoms and reduce flare-ups.