Connective tissue diseases are a group of disorders that affect the tissues supporting organs and other parts of the body. These diseases can impact the skin, joints, blood vessels, and internal organs, leading to inflammation and damage. Common examples include lupus, rheumatoid arthritis, and scleroderma. The exact cause of connective tissue diseases is often unknown, but they may involve genetic, environmental, and immune system factors. Symptoms can vary widely, ranging from joint pain and fatigue to skin rashes and organ dysfunction. Early diagnosis and treatment are essential for managing these conditions effectively.