Kidney damage refers to the impairment of the kidneys, which are vital organs responsible for filtering waste and excess fluids from the blood. When the kidneys are damaged, they may not function properly, leading to a buildup of toxins in the body. This condition can result from various factors, including high blood pressure, diabetes, and certain medications. Symptoms of kidney damage can include fatigue, swelling in the legs and ankles, and changes in urine output. If left untreated, kidney damage can progress to kidney failure, requiring treatments such as dialysis or a kidney transplant to manage the condition effectively.