Glyoxalase II is an enzyme that plays a crucial role in the detoxification of harmful compounds in the body. It is part of the glyoxalase system, which helps convert toxic byproducts of metabolism, such as methylglyoxal, into less harmful substances. This process is essential for maintaining cellular health and preventing damage from reactive compounds. The enzyme works by catalyzing the hydrolysis of S-D-lactoylglutathione to produce glutathione and D-lactate. This reaction is vital for regulating levels of reactive carbonyl species, which can lead to cellular stress and contribute to various diseases if not properly managed.