Glutathione peroxidases are a family of enzymes that play a crucial role in protecting cells from oxidative damage. They catalyze the reduction of hydrogen peroxide and other peroxides, using glutathione as a substrate. This process helps maintain cellular health by neutralizing harmful reactive oxygen species. These enzymes are found in various organisms, including humans, and are important for maintaining the balance of antioxidants in the body. There are several types of glutathione peroxidases, each with specific functions and tissue distributions. Their activity is vital for processes such as detoxification and inflammation regulation.