Excessive glutamate refers to an overabundance of the neurotransmitter glutamate in the brain. Glutamate plays a crucial role in sending signals between nerve cells, but when present in high levels, it can lead to overstimulation of neurons. This overstimulation may contribute to various neurological conditions, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. High levels of glutamate can also result in a phenomenon known as excitotoxicity, where nerve cells become damaged or die due to excessive activation. This process can disrupt normal brain function and is associated with symptoms such as cognitive decline, memory loss, and mood disorders. Managing glutamate levels is essential for maintaining overall brain health.