Connexins are a family of proteins that form channels called gap junctions between adjacent cells. These channels allow for the direct transfer of ions and small molecules, facilitating communication and coordination between cells. Connexins play a crucial role in various physiological processes, including heart function, neuronal signaling, and tissue homeostasis. There are several types of connexins, each designated by a specific number, such as connexin 43 or connexin 26. The specific type of connexin present can influence the properties of the gap junctions and the types of signals that can be exchanged, impacting overall cellular behavior and function.