Coagulative necrosis is a type of tissue death that occurs when blood supply is lost, often due to factors like ischemia or infarction. This process leads to the denaturation of proteins, causing the affected tissue to become firm and pale. It is commonly seen in organs such as the heart and kidneys. In coagulative necrosis, the cellular architecture remains relatively intact, but the cells lose their function. The dead tissue may eventually be replaced by scar tissue through a process called repair. This type of necrosis is often associated with conditions like myocardial infarction, where heart tissue is damaged due to lack of blood flow.