c-KIT is a type of protein that acts as a receptor on the surface of certain cells in the body. It plays a crucial role in cell signaling, which helps regulate processes like cell growth, survival, and differentiation. c-KIT is particularly important in the development of blood cells and is involved in the function of mast cells, which are part of the immune system. Mutations in the c-KIT gene can lead to various health issues, including certain types of cancer, such as gastrointestinal stromal tumors (GISTs). These mutations can cause the c-KIT protein to become overactive, leading to uncontrolled cell growth. Understanding c-KIT is essential for developing targeted therapies for these conditions.