A Gastrointestinal Stromal Tumor (GIST) is a type of tumor that occurs in the digestive tract, most commonly in the stomach or small intestine. These tumors arise from interstitial cells of Cajal or precursor cells, which are part of the digestive system's nerve network. GISTs can be benign or malignant and may cause symptoms like abdominal pain, bleeding, or obstruction. Diagnosis typically involves imaging tests and a biopsy to confirm the presence of the tumor. Treatment often includes surgery to remove the tumor, and targeted therapies like imatinib may be used for advanced cases. Regular follow-up is essential to monitor for recurrence.