Alpha-gal syndrome is an allergic reaction to a carbohydrate called galactose-alpha-1,3-galactose, found in red meat and some other animal products. This condition often develops after a person is bitten by a tick, particularly the Lone Star tick in the United States. Symptoms can include hives, stomach pain, and difficulty breathing, typically occurring several hours after consuming meat. Diagnosis usually involves a blood test to check for specific antibodies. Management primarily includes avoiding red meat and products containing alpha-gal. Awareness of this syndrome is important, especially in areas where tick bites are common.