Thrombotic Thrombocytopenic Purpura (TTP) is a rare blood disorder characterized by the formation of small blood clots throughout the body's small blood vessels. This condition leads to a decrease in the number of platelets, which are essential for normal blood clotting, resulting in symptoms such as bruising, fatigue, and organ damage. TTP is often caused by a deficiency of the enzyme ADAMTS13, which helps regulate blood clotting. Without this enzyme, large von Willebrand factor proteins accumulate, promoting excessive clotting. Prompt diagnosis and treatment, typically involving plasma exchange and immunosuppressive therapy, are crucial for managing TTP effectively.