"Thiazide-like" refers to a class of medications that share similar properties to traditional thiazide diuretics, which are commonly used to treat high blood pressure and fluid retention. These drugs work by promoting the excretion of sodium and water through the kidneys, helping to lower blood volume and reduce blood pressure. Examples of thiazide-like medications include chlorthalidone and indapamide. While they are not chemically classified as thiazides, they exhibit comparable effects and are often used in similar clinical situations. Their effectiveness in managing hypertension makes them a valuable option in cardiovascular treatment plans.