Thiazide-like diuretics are a class of medications primarily used to treat high blood pressure and fluid retention. They work by promoting the excretion of sodium and water from the kidneys, which helps to lower blood volume and reduce blood pressure. Common examples include chlorthalidone and indapamide. These diuretics are often preferred for their effectiveness and longer duration of action compared to traditional thiazide diuretics. They can also help prevent complications related to hypertension, such as heart disease and stroke. However, they may cause side effects like electrolyte imbalances and dehydration, so monitoring is essential.