TGF-beta Superfamily
The TGF-beta Superfamily is a group of proteins that play crucial roles in regulating various biological processes, including cell growth, differentiation, and immune responses. This superfamily includes several important cytokines, such as Transforming Growth Factor-beta (TGF-beta), Bone Morphogenetic Proteins (BMPs), and Activins, which interact with specific receptors on cell surfaces to initiate signaling pathways.
Members of the TGF-beta Superfamily are involved in numerous physiological functions, such as embryonic development, tissue repair, and the maintenance of homeostasis. Dysregulation of these proteins can lead to various diseases, including cancer and fibrosis, highlighting their significance in health and disease management.