Preimplantation Genetic Testing for Monogenic Disorders
Preimplantation Genetic Testing for Monogenic Disorders (PGT-M) is a procedure used during in vitro fertilization (IVF) to identify genetic conditions in embryos. This testing focuses on specific single-gene disorders, such as cystic fibrosis or sickle cell disease, allowing parents to select embryos free from these inherited conditions before implantation.
The process involves creating embryos through IVF and then testing a few cells from each embryo for genetic mutations. Only embryos that do not carry the targeted genetic disorder are chosen for transfer to the uterus, increasing the chances of a healthy pregnancy and reducing the risk of genetic diseases in the child.