Phospholipid Scramblase 2 (PLSCR2) is a protein that plays a crucial role in the movement of phospholipids between the inner and outer leaflets of cell membranes. This process is essential for various cellular functions, including apoptosis, blood coagulation, and cell signaling. PLSCR2 helps maintain membrane asymmetry, which is vital for cell health and communication. PLSCR2 is part of a larger family of scramblases that facilitate the bidirectional transport of lipids. It is particularly important during events like cell activation and stress responses, where rapid changes in membrane composition are required. Understanding PLSCR2 can provide insights into its role in diseases and potential therapeutic targets.